UNTARGETED METABOLOMICS

Untargeted metabolomics, also called discovery metabolomics, usually involves the comparison of the metabolome between the control and test groups, to identify differences between their metabolite profiles which may be relevant to specific biological conditions.

Whole Genome Resequencing

There are usually three steps in the experimental workflow:

  • Profiling in order to seek the metabolites with statistically significant variations in abundance within a set of experimental and control samples
  • Comprehensions as the last step which makes connections between the identified metabolites and the biological processes.
  • Determination of metabolite ID, including the chemical structure;

In the workflow of discovery metabolomics, analytical reproducibility is critical for expression profiling work; annotation is a tentative identification based on an accurate mass match to a database or a spectral match to a library; the collected data can be interpreted for biomarker discovery, biological signature/fingerprint selection and pathway mapping. Above are the most important parts in untargeted metabolomic research.

With integrated set of separation, characterization, identification and quantification systems featured with excellent robustness & reproducibility, high and ultra-sensitivity, NGB Diagnostics provides reliable, rapid and cost-effective Untargeted Metabolomics as below.

  • Cerebrospinal Fluid Untargeted Metabolomics
  • Cerebrospinal Fluid Untargeted Metabolomics
  • Serum Untargeted Metabolomics
  • Urine Untargeted Metabolomics